The new method has already been applied to rats. It can improve outcomes in the treatment of cancer and neurological diseases.
Scientists at the University of Michigan in the US have developed a non-invasive sonic technology that destroys liver tumors in rats, kills cancer cells and encourages the immune system to prevent further spread. Scitech Daily writes about it.
It was noted that this success could lead to improved cancer treatment outcomes in humans.
“By destroying only 50% to 75% of the liver tumor volume, the rat’s immune system was able to remove the rest without signs of recurrence or metastasis in more than 80% of the animals. we don’t target the entire tumor, we can still cause tumor regression, and also reduce the risk of metastasis in the future, ”said Zhen Xu, professor of biomedical engineering at UM and corresponding author of oncology studies.
The researchers developed histotripsy, a method of ultrasonic ablation using controlled cavitation. Histotripsy is the first non-invasive, non-ionizing and non-thermal method of image-guided ablation.
An experiment in rats showed that the treatment stimulated the immune response of the animals, promoting the eventual return of the non-target part of the tumor and preventing further spread of the cancer.
The essence of the treatment lies in the non -invasive focusing of ultrasonic waves for mechanical destruction of the target tissue with an accuracy of up to one millimeter.
“Histotripsy is a promising option that can transcend the limitations of currently available ablation techniques and provide safe and effective non-invasive removal of liver tumors. We hope that our findings from the This study will motivate future preclinical and clinical histotripsy studies to achieve the true goal of clinical implementation of histotripsy treatment in liver cancer patients, ”said Tejasvi Vorlikar, a mag doctoral studies in biomedical engineering.
Waves of treatment work without the harmful effects of modern techniques such as radiation therapy and chemotherapy.
“Our transducer, designed and manufactured by UM, delivers high -amplitude ultrasonic pulses of microsecond duration – acoustic cavitation – to focus on the tumor specifically for its destruction. Traditional ultrasound devices use lower amplitude pulse for imaging, “added the study authors.
In particular, the long microsecond pulse from the UM sensor generates microbubbles in the target tissues. Thus mechanical stresses kill cancer cells and destroy the tumor structure.
Remember that liver cancer is one of the top 10 causes of cancer deaths worldwide and in the United States. Of the many treatment options, the prognosis remains weak, with a five -year survival rate in the US of less than 18%.
We will recall, earlier British scientists have demonstrated the viability of technology for the treatment of tumors. The method is based on the magnetic effect on malignant cells.
The first modern device for cancer treatment appeared in Khmelnitsky
News from Athletistic in the Telegram. Subscribe to our channel Athletistic
Source: korrespondent
