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Addiction-causing signals in the brain discovered

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Increased levels of certain proteins in the brain cause difficulty with self-control and concentration.

Researchers from the University of Michigan have found signals in the brain that cause addictions to develop in humans. The results of the scientists’ work were published in the journal eNeuro.

In their study, the scientists focused on the relationship between the brain’s choline transporter, cytokines, and signaling differences in a rat animal model.

“Choline is a cell membrane protein needed to control attention, while cytokines are proteins that stimulate or suppress the immune system. The behavior of 197 animals was studied using the Pavlovian conditioned approach (PCA ) testing in consecutive sessions lasting more than five days,” the scientists said.

According to them, animals with poor attentional control when choosing accents developed strong cravings, which were triggered by brain signals.

“Subjects with poor functioning of choline transporters and high levels of cytokines have difficulty controlling attention,” they added.

Thus, the researchers caused an artificial increase in the level of cytokines and found an important connection between their increased production and a decrease in the function of transporting choline.

“This contributes to impaired attention control and addiction,” the researchers concluded.

Recall that earlier in Switzerland, scientists at the University of Geneva investigated the mechanism of cocaine addiction and found that it appears due to an imbalance in the brain of two neurotransmitters – dopamine and serotonin.

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Source: korrespondent

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