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Ivermectin Has No Significant Effect in COVID Treatment, US Study Finds

Ivermectin, a popular anti-parasite drug as a home remedy for COVID-19 Warnings The Food and Drug Administration has found no significant effect in reducing symptoms or reducing the incidence of hospitalization or death; According to the results of a clinical study released on Sunday.

The research, led by Duke University and Vanderbilt University Science, included 1,591 participants who received 400 mcg / kg of ivermectin, which is often used to treat cattle, or placebo. Fifty -seven percent of participants said they had received at least two doses of COVID vaccine.

This clinical study has not been evaluated.

The primary measure of the effectiveness of ivermectin used in the study was based on continued recovery over time, defined as three consecutive days without symptoms of COVID. Major secondary outcomes included hospitalization or cumulative death within 28 days, Susanna Nagy, MD, MHS, one of the investigators involved in the study, wrote in a paper reviewing the results of study.

Taking ivermectin for three days ”resulted in a reduction in symptoms in less than one day and did not reduce hospitalization or death in outpatients with COVID-19 in the United States during the Delta and Omicron, ”he said. the document.

This clinical trial was part of the Accelerated COVID-19 Therapeutic Interventions and Vaccines (ACTIV) -6 study group, which examined whether certain FDA-approved drugs could be effective in treating patients. over age 30 with early mild to mild COVID. moderate. .

“ACTIV-6 adds to the growing evidence that there is no clinically associated therapeutic effect of ivermectin at this dose and duration,” Nagy wrote. “Although individuals with severe symptoms initially appeared to have a beneficial therapeutic effect with ivermectin placebo, this subgroup is small, so these findings should be considered exploratory.

The results of this study are consistent with the results of another large clinical study in Brazil published by the New England Journal of Medicine in May.

“Ivermectin treatment did not result in an increased frequency of hospital admissions in outpatient patients with an early diagnosis of COVID-19 due to the development of COVID-19 or prolonged emergency department follow-up , “the researchers concluded.

Although the drug has significant side effects against COVID, despite the lack of evidence, ivermectin has important enhancers, including the Joe Rogan podcast.

Rogan shared the story on Twitter in February, claiming the drug was effective against the Omicron variant in a Phase III clinical trial. Rogan deleted the tweet after it turned out to be incorrect.

Last year, Rogan said he has been taking medication since testing positive for covidium in September 2021 as a remedy.

A month earlier, the FDA issued a warning on Twitter not to self -medicate with ivermectin, which is commonly used in animals.

“You are not a horse. You may not. Seriously, you. “Stop it,” the agency wrote on Twitter in August 2021.

The FDA also published a detailed post on their website, in which they explained why Americans should avoid the drug.

In Arkansas, inmates filed a lawsuit against a doctor who inadvertently prescribed medications as treatment for COVID. The northwestern state, however, issued a resolution praising the doctor in February.

Source: Huffpost

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