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A “humanized” porcine kidney model makes xenografting more realistic

Publications are piling up, and transplanting organs from genetically modified animals is looking more and more realistic. Researchers from Harvard University and the American company eGenesis publish in a scientific journal Nature results of transplants performed on non-human primates with a pig kidney model consisting of a unique combination of genetic modifications. The resulting survival times (up to two years) are the longest to date. Data that could pave the way for human trials in the coming months if the FDA, America’s medical regulator, gives the green light.

A real chance of survival

The race is accelerating among research groups working on kidney xenografts. And this publication could mark an important turning point. “This is a great article and I think it’s going to get a lot of buzz“, comments Valentin Guthaudien, nephrologist and researcher at the Institute of Organ Transplantation and Regeneration.

Source: Le Figaro

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