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RNA vaccines. how two researchers’ persistence won them a Nobel Prize

It is a story of intuition, persistence and encounter. This Monday, Hungarian biochemist Katalin Kariko and American doctor Drew Weissman received the Nobel Prize in Medicine. for discoveries about nucleoside base modifications that enabled the development of effective mRNA vaccines against Covid-19 »announced the Nobel Committee.

Ten years ago I was fired and forced to retire »Katalin Cariko said after a few hours. Born in communist Hungary, she left for the USA in 1985 with her husband, 2-year-old daughter and 1,000 euros hidden in a teddy bear, she worked alone for a long time with one conviction: When trying to modify DNA, it was better to look at messenger RNA (mRNA); The “spokesman” of DNA, it is responsible for conveying the “recipes” necessary for the production of proteins to the cell. DNA is, of course, more stable…

Source: Le Figaro

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