The advent of immunosuppressants in 1982 with cyclosporine and then in 1995 with tacrolimus enabled the development of organ transplantation, primarily kidney transplantation, permanently blocking graft rejection. According to the Biomedical Agency, France has more than 40,000 kidney transplant recipients, which is constantly increasing.
But immunosuppressants have serious side effects. by greatly reducing the activation of immune cells, they facilitate infections, increase the risk of cancer, complicate vaccinations, and “ affect the function of other organs, with an increased risk of cardiovascular problems and diabetes, as well as long-term toxicity to the kidneys, which compromises the lifespan of vaccines by 14. years average currently “, says Pierre Marché, Director of Inserm Pharmacology and Transplantation at Limoges University Hospital.
But new antibody-based treatments are coming that target many…
Source: Le Figaro
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