BUT hospital medical team NYU Langone Health (New York, USA) successfully transplanted hearts from pork genetically modified drugs to two recently deceased people who remained on life support machines with respirators, the center said Tuesday.
Nader Moazami, Head of the Department of Heart Transplant Surgery. hospitalsupervised interventions carried out in June and July of this year, during which animal organs were integrated into two brain-dead donors and their operation was observed for three days.
The experiment repeats a similar experiment conducted last year in University of Marylandin which a genetically modified porcine heart was first implanted in a patient with terminal heart disease but who died 49 days later as his condition worsened.
According to NYU Langone’s note, in these two cases xenotransplantation (animal-to-human transplant) no early signs of rejection were observed and the hearts functioned normally on standard post-transplant preparations and without additional mechanical support.
The process followed a new infectious disease protocol that eliminated the presence of porcine endogenous retrovirus (pCMV) and strict measures were applied to prevent and monitor potential zoonotic transmission of porcine endogenous retrovirus (PERV).
Director of the Institute of Transplantology of the hospital Robert Montgomery, responsible for graft from bud from pork changed to a man who died late last year, believes monitoring of swine viruses included in this process was a key element of his success.
hearts The pigs were from the biotech company Revivicor and had ten genetic modifications to prevent organ rejection, abnormal growth in the body, and incompatibility between animal and human.
Montgomery said donor research has recently late they are necessary to collect data on people necessary for the development of a field of medicine that for decades and until last year only experimented on primates.
The hospital noted that these xenotransplantation The successful cases are a step towards developing a protocol to provide alternative organ supply for people with fatal heart disease at precisely the time of organ shortage in state joined.
EFE
Source: RPP
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