The melatonin receptor MT1 could be the basis for new treatments for sleep disorders, Parkinson’s disease and dementia, which affect memory, emotions and dreams.
Scientists have discovered that the melatonin receptor MT1 is a key regulator of REM sleep, responsible for dreaming, emotional regulation and memory consolidation. It was reported by Neuroscience News.
The discovery could be a breakthrough in the development of new treatments for sleep and conditions such as Parkinson’s disease and dementia, which are associated with REM sleep disturbances.
According to researchers, human sleep consists of a sequence of stages, each of which performs different physiological functions. REM sleep plays an important role in cognitive processes, while non-REM sleep ensures physical recovery of the body. Disturbances in this cycle can have a negative impact on cognitive function and increase the risk of neuropsychiatric disorders.
The study, published in the Journal of Neuroscience, is the first to identify a specific receptor that regulates REM sleep. Until now, scientists have not been able to determine which receptor is responsible for this phase. Currently there are no drugs aimed at improving REM sleep, since most existing sleeping pills reduce its duration.
A team of researchers from the University of Padua, led by Professor Stefano Comai, discovered that MT1 affects neurons in an area of the brain known as the Locus Coeruleus, which controls the release of the hormone norepinephrine. Using a special drug that activates MT1, scientists were able to increase the duration of REM sleep in experimental animals.
This discovery provides hope for the development of a targeted drug for people with sleep disorders, which will improve their quality of life and reduce the risks of developing cognitive and emotional disorders. .
It was previously reported that the best sleeping positions have been established, which can have a positive effect on the quality of our rest and the general condition of the body.
Source: korrespondent
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