Cumulative use of proton pump inhibitors (PPIs) for more than 4.4 years can increase the risk of dementia by 33% in people over the age of 45. These alarming conclusions were made in an American study conducted on 5,712 volunteers from an American group and published on August 9 in a scientific journal. Neurology .
” This study is of good quality, but it is observational and therefore cannot prove causation. It is, however, a new reminder that PPIs should only be prescribed for a limited period of time, between 4 and 12. weeks usually – commented Pr: Jean-Louis Frossard, Head of the Department of Gastroenterology at the University Hospitals of Geneva.
This is also the international recommendation recalled in 2022 by the High Health Authority (HAS) in the Good Use Sheet. However, these molecules (omeprazole, esomeprazole, pantoprazole, lansoprazole and rabeprazole) remain…
Source: Le Figaro
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