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Multiple sclerosis. genetic traces to understand the most difficult cases

Why do some people with multiple sclerosis see the disease progress to disability more quickly than others? The question excites doctors and longtime researchers because the stakes are high. This autoimmune disease, which affects 100,000 people in France (three-quarters of them women), is the second leading cause of disability in young people after road traffic accidents.

Remember that multiple sclerosis has two components: one is more inflammatory, characterized by “flares” of various symptoms that are temporary and variable in nature and frequency from one individual to another: decreased visual acuity, balance disorders, muscle weakness, tingling. Another aspect of the disease, partly independent of these outbreaks, is neurodegeneration, which begins very early; the body “attacks itself” through the immune system and destroys myelin, the sheath that protects axons…

Source: Le Figaro

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