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The microbiota of the future, the antidepressant?

Mental illness also originates in… the digestive tract. When our microbiota is disrupted, unwanted bacterial families colonize the gut and produce inflammatory molecules. “Under their action, the digestive wall becomes porous. proteins that shouldn’t get out of it join the bloodstream and trigger an immune-inflammatory cascade that eventually reaches the brain.”explains Dr: Riad Tamouza, researcher and immunologist at Henri-Mondor Hospital (Creteil).

In depression, 20% to 30% of patients are resistant to antidepressants, and it is hypothesized that dysbiosis may explain some or all of these resistant depressions. Hence the idea of ​​restoring a beneficial relationship between humans and the 50,000 billion bacteria that live in their guts. This is the Promood project, carried out within the framework of the FondaMental Foundation with the start-up Ginov and researcher Joël Dore at the National Research Institute…

Source: Le Figaro

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