Researchers have studied the protein responsible for the formation of the virus and consider every structural detail.
Scientists from the Scripps Research Institute, specializing in microscopy and vaccine development, Lisa Ashun-Wilson and Alba Torrents de la Peña, using new technologies, visualized the molecular structures of the protein responsible for in the development of hepatitis C virus. Inverse writes about it.
Thus, it is possible to understand how the virus works, which will help in the development of a vaccine against hepatitis C.
In the past, the main problem was that this protein called HCV E1E2 was very flexible and fragile.
It can change shape frequently and is easily damaged.
The researchers did this using cryoelectron microscopy. This type of imaging method allows you to quickly freeze water without it crystallizing. So the protein is enclosed in a glass frame.
As a result, scientists were able to study the protein and analyze every detail of its structure.
They also inserted the genetic code to create HCV E1E2 into human cells, which made it possible to obtain enough protein for study. It was then cleaned and immersed in liquid ethane for rapid freezing, and then in liquid nitrogen to prevent structural damage.
At the end, the researchers obtained a 2D image, which they converted into a 3D model.
So they learned more about its functions that were necessary for the development of a hepatitis C vaccine.
Remember that hepatitis of unknown origin is registered in the world, the number of cases is increasing.
Scientists have discovered the cause of hepatitis outbreaks in children
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Source: korrespondent
I am Ben Stock, a passionate and experienced digital journalist working in the news industry. At the Buna Times, I write articles covering technology developments and related topics. I strive to provide reliable information that my readers can trust. My research skills are top-notch, as well as my ability to craft engaging stories on timely topics with clarity and accuracy.