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When the brain gets tired, glutamate builds up

You work on a file for several hours and start to accumulate errors. you’re on the second sweet and you’ve just yelled at a co-worker. All these signs confirm that your brain is tired and your cognitive control is significantly reduced. Studied since the end of XIXe century, cognitive fatigue remains poorly understood and the mechanisms responsible for it are still unknown. A French research team recently published in a scientific journal Current Biology results that shed new light on this phenomenon.

“Before, there were two types of hypotheses to explain this fatigue. Functional theory believes that fatigue is a signal from the brain to stop a stressful activity in order to move on to a more enjoyable activity. explains Mathias Pesillon, Research Director of the Brain Institute (ICM – Hôpital de la Salpêtrière) and the person in charge of this project. “But…

Source: Le Figaro

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