The Y chromosome, which is only present in humans, can disappear with age. If it may come as a surprise, the fact has been known for a long time. This genetic abnormality, which does not affect all men or all cells in the body, has long been considered a simple marker of aging.
However, in recent years, numerous studies have shown that men who lose their Y chromosome have a shorter life expectancy and an increased risk of cancer, cirrhosis and Alzheimer’s disease. Simple association or true causation? Until now, the issue remains unresolved.
Genetic desert
Research published in a journal Science provides the beginning of an answer, elegantly showing how this chromosomal loss impairs cardiac function. An important discovery that can open new perspectives for the research of age-related pathologies in men.
The authors of this paper include Lars Forsberg, researcher…
Source: Le Figaro
