Contrary to popular opinion, tuberculosis is not a disease of the past. Although France is spared, it kills 1.3 million people worldwide each year, mostly in countries with high levels of poverty. Nowadays, the treatment of this disease remains a real obstacle. The usual treatment involves taking a cocktail of antibiotics for several months. But because of the increasing number of antibiotic-resistant forms, treatment can last up to 24 months and involve up to 23 pills a day. The development of effective and faster treatment is therefore one of the main challenges to eliminate tuberculosis by 2030, according to the goals set by the United Nations conference in New York in September 2023.
Among the candidates, BPaL, a combination of three antibiotics (bedaquiline, pretomanid and linezolid) to be taken for six months, has already been approved by the US Food and Drug Administration (FDA)…
Source: Le Figaro

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